Dr. Dominique Piquette: 2026 PSI Mid-Career Knowledge Translation Fellowship Recipient

“The SSPARK (Sourcing, Synthesizing, Presenting, and Applying Research Knowledge) Project will improve the health of Ontarians by ensuring that the best available evidence is consistently applied in critical care settings across the province. By embedding knowledge translation and continuing professional development within day-to-day clinical practice, SSPARK will reduce persistent knowledge-to-practice gaps, enhance clinicians’ competence, and support more reliable delivery of evidence-based care. Its cross-institutional model will strengthen collaboration between academic and community ICUs, reduce inequities in access to new knowledge, and foster a sustained culture of learning and quality improvement. Ultimately, this initiative is expected to lead to safer, more effective critical care and better patient outcomes for Ontarians.” – Dr. Dominique Piquette

PSI Foundation is pleased to announce Dr. Dominique Piquette as the recipient of the 2026 PSI Mid-Career Knowledge Translation Fellowship.

About Dr. Dominique Piquette

Dr. Dominique Piquette is currently a Staff Physician in the Department of Critical Care Medicine of the Sunnybrook Health Sciences Centre; Scientist at the Sunnybrook Research Institute; and Associate Professor in the Interdepartmental Division of Critical Care Medicine of the University of Toronto. She is also an Education Scholar at the Wilson Centre (a research institute in healthcare education), and co-Program Director of the Sepsis Canada/LifTING Health Research Training Platform.

Dr. Piquette’s research focuses on better understanding how physicians learn in changing critical care clinical environments at the postgraduate and post-certification levels. She uses a range of research methodologies, including quantitative, qualitative, and mixed methods approaches.

About the PSI Mid-Career Knowledge Translation Fellowship

The PSI Mid-Career Knowledge Translation Fellowship is intended to provide salary support for a mid-career physician researcher in Ontario, who has demonstrated the ability to successfully complete high impact knowledge translation research. The total amount of the award is $400,000 over two or three years, with the sponsoring institution providing matching funding, contributing to 50% of the total award.

PSI acknowledges that mid-career can be a challenging time for physician researchers. During this phase, there are often additional academic roles and responsibilities including committee work, leadership positions, and mentoring of junior investigators, while clinical work continues. PSI recognizes the importance in supporting this phase of an investigator’s trajectory.

Dr. Piqutte highlights the importance of salary support awards for mid-career physician researchers:

“Mid-career salary support is crucial for sustaining meaningful research programs and ensuring that early-career momentum translates into long-term impact. At this stage, clinician-investigators are simultaneously advancing complex research portfolios, mentoring the next generation of scientists, contributing to national innovation and health-system priorities, and fulfilling essential clinical and administrative roles. Stable salary support allows them to protect the time necessary to conduct high-impact research, pursue innovative or higher-risk ideas, and maintain the continuity required for longitudinal programs that deliver tangible benefits to Ontarians. Yet funding opportunities for mid-career investigators remain particularly scarce and highly competitive. Without sustained investment in this critical segment of the health research community, Ontario risks weakening its capacity to generate the evidence needed to improve healthcare quality and population health.”

Fellowship Funds to be Used to Improve the Quality and Safety of Care for Critically Ill Patients in Ontario

Critical care research in Canada has led to many discoveries that improve the care for seriously ill patients. However, these research findings do not always reach the bedside quickly. This “knowledge-to-practice gap” means that patients may not always receive the best or most up-to-date care. The gap exists for many reasons — new evidence is produced faster than clinicians can absorb it, traditional education sessions are often too general, and every hospital has its own routines and challenges.

To help close this gap, Dr. Piquette’s team is developing the SSPARK Unit — short for Sourcing, Synthesizing, Presenting, and Applying Research Knowledge. SSPARK will bring together researchers, healthcare providers, and patients to identify new evidence, summarize it in simple formats, and share it directly with intensive care teams. The unit will work with hospitals across Ontario to adapt this information to their local needs and help staff use it in daily practice.

By making research easier to understand and apply, SSPARK aims to improve the quality and safety of care for critically ill patients. It will also build stronger connections between hospitals and researchers, helping ensure that life-saving discoveries benefit patients everywhere, not just in research centres.

Dr. Andrea Gershon: 2026 PSI Mid-Career Knowledge Translation Fellowship Recipient

“As Ontario’s health-care system faces unprecedented pressure, remote clinical monitoring offers a transformative path forward. Supported by the PSI Mid-Career Knowledge Translation Fellowship, my research and knowledge translation will ensure this inevitable shift delivers care that is patient-centred, equitable, safe, and clinically meaningful.” – Dr. Andrea Gershon

PSI Foundation is pleased to announce Dr. Andrea Gershon as the recipient of the 2026 PSI Mid-Career Knowledge Translation Fellowship. 

About Dr. Andrea Gershon

Dr. Andrea Gershon is a Respirologist and Senior Scientist at Sunnybrook Health Sciences Centre, University of Toronto and ICES.

Dr. Gershon’s award-winning research and knowledge translation program uses ‘Big Data’ to learn from the real-world experiences of people living with lung disease, with a focus on vulnerable groups. Her clinical studies evaluate the use of remote monitoring and wearables in people with respiratory disease.

Dr. Gershon enjoys working with junior faculty, postgraduate fellows, graduate candidates, and other students at all levels of training. She has a passion for supporting these upcoming leaders, researchers, and clinicians who are the future of discovery and innovation to improve respiratory health worldwide.

About the PSI Mid-Career Knowledge Translation Fellowship

The PSI Mid-Career Knowledge Translation Fellowship is intended to provide salary support for a mid-career physician researcher in Ontario, who has demonstrated the ability to successfully complete high impact knowledge translation research. The total amount of the award is $400,000 over two or three years, with the sponsoring institution providing matching funding, contributing to 50% of the total award.

PSI acknowledges that mid-career can be a challenging time for physician researchers. During this phase, there are often additional academic roles and responsibilities including committee work, leadership positions, and mentoring of junior investigators, while clinical work continues. PSI recognizes the importance in supporting this phase of an investigator’s trajectory.

Dr. Gershon highlights the importance of salary support awards for physician researchers at the mid-career level:

“Mid-career salary support is a smart investment. It gives physician researchers the time and resources to lead, mentor the next generation, and turn their expertise into real improvements in patient care, health equity, and a stronger, more sustainable health system. I am very grateful for this PSI Mid-Career Knowledge Translation Fellowship.”

Fellowship Funds to be Used to Improve the Health and Health Equity for People with Respiratory and Other Chronic Diseases

Canada’s healthcare system is facing increasing strain as the population ages and more people live with chronic illnesses including heart and lung disease. Hospitals and clinics are often overwhelmed, leading to long wait times and barriers to accessing timely, high-quality care—particularly in rural, remote, and underserved communities. To address these challenges, remote clinical monitoring (RCM) is emerging as a transformative approach. RCM uses connected technologies—such as smartphones, smartwatches, and wearable sensors like Fitbits—to continuously track health indicators including breathing, oxygen levels, sleep, and heart rate from home. This data allows healthcare teams to identify issues early, adjust treatment plans in real time, and provide proactive support between in-person visits, helping reduce emergency department use and prevent hospitalizations.

Dr. Gershon has developed a comprehensive RCM platform to accelerate innovation in this field across Ontario and beyond. The system integrates a patient-friendly mobile app, wearable sensors, and a secure clinician dashboard that facilitates continuous, data-driven care. Her goal is to use RCM to make healthcare more personalized, efficient, and equitable for all Canadians. This includes mentoring trainees to strengthen national research capacity and advance the science and practice of RCM.

Dr. Sophiya Benjamin: 2026 PSI Mid-Career Knowledge Translation Fellowship Recipient

“Insomnia affects one in five Ontarians, with the burden falling disproportionately on women and the socioeconomically disadvantaged. The impacts extend beyond poor sleep as people with insomnia experience reduced quality of life, workplace accidents, and significant health care costs. In Canada, insomnia’s economic impact reaches $1.9 billion in direct and indirect health care costs, with annual GDP losses estimated at $26 billion. While a specialized talk therapy for insomnia called CBT-I is a safe and highly effective treatment, access to trained therapists remains limited. Because of this gap, many rely on potentially harmful prescription medications or over-the- counter remedies. Through this fellowship, I will translate Ontario’s new Quality Standard for Insomnia into practical tools for health and social providers across primary care and adapt these principles to create resources and programs tailored to older adults in long-term care, and those living with dementia. By equipping clinicians with evidence-based approaches and reducing reliance on potentially harmful medications, this work will improve health outcomes, safety and quality of life for Ontarians.” – Dr. Sophiya Benjamin

PSI Foundation is pleased to announce Dr. Sophiya Benjamin as the recipient of the 2026 PSI Mid-Career Knowledge Translation Fellowship.

About Dr. Sophiya Benjamin

Dr. Sophiya Benjamin is Geriatric Psychiatrist and Associate Professor in the Department of Psychiatry and Behavioural Neurosciences at McMaster University. She is the Schlegel Chair in Mental Health in Aging at the Schlegel-UW Research Institute for Aging (RIA) and the Co-Founder and Co-Executive Director of GeriMedRisk, a publicly funded, not-for-profit organization that optimizes medication use in older adults through clinical consultations across Ontario and the education of clinicians both nationally and internationally. She is on the medical staff of Waterloo Regional Health Network, and her clinical practice is in the Kitchener-Waterloo Region.

Her work is dedicated to addressing system-level challenges in the care of older adults, focusing on implementing and integrating evidence-informed solutions for issues such as polypharmacy and insomnia.

About the PSI Mid-Career Knowledge Translation Fellowship

The PSI Mid-Career Knowledge Translation Fellowship is intended to provide salary support for a mid-career physician researcher in Ontario, who has demonstrated the ability to successfully complete high impact knowledge translation research. The total amount of the award is $400,000 over two or three years, with the sponsoring institution providing matching funding, contributing to 50% of the total award. 

PSI acknowledges that mid-career can be a challenging time for physician researchers. During this phase, there are often additional academic roles and responsibilities including committee work, leadership positions, and mentoring of junior investigators, while clinical work continues. PSI recognizes the importance in supporting this phase of an investigator’s trajectory.

Dr. Benjamin highlights the significance of salary support awards for physician researchers at the mid-career level conducting knowledge translation research:

“Salary support awards, particularly for knowledge translation, are an investment that ensures important research doesn’t remain confined to the lab or journal but is mobilized for clinicians and policymakers and ultimately benefits patients. These awards provide protected time and strategic support to physician researchers, helping us bridge this gap and ensure the implementation of high-impact research that improves health outcomes for people across Ontario.”

Fellowship Funds to be Used to Improve Sleep Health for Older Adults in Ontario

Dr. Benjamin’s fellowship work extends from her experience with GeriMedRisk. Beginning with a stepped wedge randomized controlled trial in 2017, it showed decreased harmful medication use and hospital avoidance while reducing wait times for older adults to receive specialist expertise. This evidence led to sustainable funding from the Ontario Ministry of Health, enabling GeriMedRisk to spread and scale across Ontario. GeriMedRisk was recognized in Canada’s National Dementia Strategy in both 2019 and 2023.

GeriMedRisk’s work with older adults on multiple medications highlighted the well-known connection between sleep disturbances and problematic sedative medication use. This informed Dr. Benjamin’s work in establishing the Older Adult Insomnia Collaborative in 2022 to address this problem across health care settings. The collaborative now has over 45 members representing expertise in multiple areas. In conjunction with this work, Dr. Benjamin co-chaired the Ontario Health Quality Standard Advisory Committee resulting in Ontario’s first Quality Standard for Insomnia in February 2025.

This fellowship will support the next phase of this work in enabling knowledge translation of Ontario’s new insomnia quality standards into practical tools, resources and programs across three key areas: integrating evidence-based sleep pathways in primary care, designing and implementing long term care specific interventions through co-design with residents and staff, and developing resources for people living with dementia and their care partners. By partnering with experts by experience, clinicians, and researchers from more than 25 organizations, this work will improve sleep health for Ontarians while reducing reliance on inappropriate medications and enabling equitable access to evidence-informed care.

Dr. Robert Simpson: 2026 PSI Graham Farquharson Knowledge Translation Fellowship Recipient

“Canada has among the highest incidence and prevalence rates for multiple sclerosis (MS) worldwide and an estimated 30,000+ people in Ontario live with MS. MS can be a highly disabling condition in it’s own right. However, most people with MS don’t just have MS; rather the majority have additional health conditions, amongst which the commonest are anxiety and depression.  Having anxiety and/or depression adds significant health challenges to people with MS.  Although effective treatments for anxiety and depression in people with MS exist, such as cognitive behavioural therapy (CBT) and Mindfulness-based interventions (MBI), access in Ontario is very limited.  In this PSI Graham Farquharson Knowledge Translation Fellowship, I will implement and evaluate evidence-based tailored CBT and MBI resources for people with MS across Ontario.” – Dr. Robert Simpson

PSI Foundation is pleased to announce Dr. Robert Simpson as the recipient of the 2026 PSI Graham Farquharson Knowledge Translation Fellowship.

About Dr. Robert Simpson

Dr. Robert Simpson is an Associate Professor in the Division of Physical Medicine and Rehabilitation at the Temerty Faculty of Medicine at the University of Toronto. He is a Specialist Physician and Clinician Investigator in Physical Medicine & Rehabilitation (PM&R). His clinical work is based between the University Health Network (Toronto Rehabilitation Institute) and Unity Health (St. Michael’s Hospital).

Dr. Simpson’s overall research encompasses helping to improve the quality of life of people living with multiple sclerosis (MS). His current research focus is on the role of psychological therapies in the care of people with MS.

About the PSI Graham Farquharson Knowledge Translation Fellowship

Knowledge translation research aims at transitioning research discoveries to the real world to improve health outcomes. The PSI Graham Farquharson Knowledge Translation Fellowship – valued at $300,000 for over two or three years – helps protect a promising new clinician investigator’s research time, allowing the Fellow to undertake high-impact translational research in Ontario.

Dr. Simpson highlights the importance of salary support for physicians at the early career level:

“The salary support award provided by PSI for this Graham Farquharson Knowledge Translation Fellowship is critical in enabling me to undertake the work proposed.  The support will protect my time to implement and evaluate tailored CBT and MBIs for people with MS across Ontario.  I will be able to dedicate my time to cementing collaborative working relationships with the specialist MS clinics across Ontario, train clinic staff to deliver these interventions, conduct rigorous analyses of effectiveness and implementation, and ensure the ultimate success of this project.”

Fellowship Funds to be Used to Improve the Psychological Care of People with MS in Ontario

People in Ontario living with multiple sclerosis (MS) often experience psychological distress. MS can be stressful for many reasons, including uncertainty about the illness and complex symptoms like low mood, low energy and physical discomfort which often get worse through stress. This creates a toxic cycle where stress worsens symptoms, symptoms worsen stress, and so on. Unfortunately, therapies to address this toxic cycle are not currently available for all Ontarians living with MS. Fortunately, Dr. Simpson’s prior research demonstrated psychological therapies can help people with MS manage symptoms of psychological distress effectively.  In this Fellowship, Dr. Simpson will translate these research findings into frontline clinical services for people living with MS across Ontario, delivering online guided self-management and group psychological therapy tailored to common issues people living with MS face. Dr. Simpson will train MS healthcare providers across Ontario to deliver these therapies and will support rollout throughout the network of specialist MS clinics across Ontario. The resources developed and rolled out will be tested in a rigorous clinical trial to see how well they work in the context of Ontario.  Resources developed through the Fellowship will be made freely available to all people living with MS in Ontario.

Dr. Archna Gupta: 2026 PSI Graham Farquharson Knowledge Translation Fellowship Recipient

“Ontario’s primary care system is facing major challenges, with many people struggling to find a family doctor or primary care clinician and access the care they need. The new Primary Care Act (2025) offers a unique opportunity to make meaningful improvements, setting out six patient-centred goals to increase access and strengthen care for all Ontarians. My research and knowledge translation activities are focused on helping Ontario’s primary care system evolve to meet these important targets. This is a critical moment for health care in our province—a chance to make lasting, positive changes that will benefit every community. My research will play a key role in making care more equitable and accessible, informing policies and tools that support patients and health professionals alike. Ultimately, this research will help support a stronger, fairer primary care system—so that every Ontarian can get the care they need, when and where they need it most.” – Dr. Archna Gupta

PSI Foundation is pleased to announce Dr. Archna Gupta as the recipient of the 2026 PSI Graham Farquharson Knowledge Translation Fellowship.

About Dr. Archna Gupta

Dr. Archna Gupta is a Scientist at Upstream Lab and Unity Health Toronto, and an Assistant Professor at the Department of Family and Community Medicine at the University of Toronto. She is a practicing family physician and family medicine obstetrics provider at St. Michael’s Hospital. Dr. Gupta’s research focuses on health system strengthening, with a particular focus on primary care and health equity.

Dr. Gupta has established herself as a productive early-career clinician-scientist, having published 25 peer-reviewed articles—16 as either first or senior author. She has also secured over $1 million in research funding as a Principal Investigator (PI) or co-PI. Her recent study on how distance to primary care affects healthcare use and quality was published in the Canadian Medical Association Journal and featured on the front page of the Toronto Star.

Dr. Gupta received her PhD in Health Services Research at the Institute of Health, Policy, Management and Evaluation at the University of Toronto (2022), her Master’s in Public Health at the Dalla Lana School of Public Health at the University of Toronto (2014) and her Medical Degree from McMaster University (2009).

About the PSI Graham Farquharson Knowledge Translation Fellowship

Knowledge translation research aims at transitioning research discoveries to the real world to improve health outcomes. The PSI Graham Farquharson Knowledge Translation Fellowship – valued at $300,000 for over two or three years – helps protect a promising new clinician investigator’s research time, allowing the Fellow to undertake high-impact translational research in Ontario.

Dr. Gupta highlights the importance of salary support awards for early career researchers:

“Salary support awards for early-career researchers, like the PSI Graham Farquharson Knowledge Translation Fellowship, are vital—they provide the protected time needed to pursue high-impact research and knowledge translation that address health system challenges. With this support, I can focus on translating research into practical solutions for Ontario’s primary care system, ensuring that the best available evidence informs policy and practice.”

Fellowship Funds to be Used to Transform Primary Care in Ontario

Ontario is facing a primary care crisis, with millions of people struggling to access primary care. This crisis affects everyone, especially vulnerable groups, and leads to more emergency visits and poorer health outcomes. To tackle these issues, my research aims to: (1) map where the greatest gaps exist between patients and primary care providers; (2) study the impact of virtual health visits on how far people need to travel for primary care; and (3) create easy-to-use resources to help people manage minor health issues themselves. By working closely with patients, primary care providers, and policymakers, these projects will help shape fair and practical solutions—like matching patients with family doctors based on where they live and making reliable self-care tools widely available. The goal is to make sure every Ontarian can get quality care when and where they need it, while decreasing unnecessary strain on the health system.

Dr. Saadia Sediqzadah: 2026 PSI Graham Farquharson Knowledge Translation Fellowship Recipient

“According to the Ontario Early Psychosis Intervention Program Standards, early phase psychosis (EPP) is defined as experiencing symptoms of a psychotic disorder between the ages of 14 and 35, who are either untreated or receiving treatment for 6 months or less. EPP can be a confusing time for a young person. The hallmark feature of psychosis is the difficulty in telling what is real and what is not. This often-persistent lack of insight has treatment implications for both the patient and their healthcare providers. Medication acceptance and adherence can be a challenge. The mainstay of treatment of psychotic illness includes antipsychotics. While effective, they carry a significant burden of metabolic syndrome, including weight gain and increased risk of diabetes. Concerns about the side effects, how long one must be on medication, or even simply accepting one has a mental illness that requires medication in the first place, can be common concerns and barriers to treatment. We lack tools to address these issues that are tailored to both prescribers and patients, especially those that include people with lived experience in the development process. As such, my proposed research will employ knowledge translation approaches to guide both patients and prescribers on psychosis treatment, as well as the prevention/management of metabolic side effects of antipsychotics.” – Dr. Saadia Sediqzadah

PSI Foundation is pleased to announce Dr. Saadia Sediqzadah as the recipient of the 2026 PSI Graham Farquharson Knowledge Translation Fellowship.

About Dr. Saadia Sediqzadah

Dr. Saadia Sediqzadah (she/her) is a psychiatrist and clinician-investigator at the Department of Psychiatry at St. Michael’s Hospital (Unity Health Toronto) and Scientist at Upstream Lab.

She specializes in early psychosis intervention, providing psychiatric care to transitional aged youth 14-35 years old with psychotic disorders. Her research is informed by her clinical practice serving this vulnerable population. Her projects focus upon shared medical decision-making in early phase psychosis and the prevention and management of metabolic side effects of antipsychotic medications.

About the PSI Graham Farquharson Knowledge Translation Fellowship

Knowledge translation research aims at transitioning research discoveries to the real world to improve health outcomes. The PSI Graham Farquharson Knowledge Translation Fellowship – valued at $300,000 for over two or three years – helps protect a promising new clinician investigator’s research time, allowing the Fellow to undertake high-impact translational research in Ontario.

Dr. Sediqzadah highlights the significance of salary support awards for physician researchers at the early career level:

“This salary support award is an absolute game changer for early career researchers like me. Trying to fit in research activities between clinics, in the evenings or weekends, while also (in my case) raising two small children, is very difficult to do. PSI’s support will allow me to protect my time so that I can focus on my research and knowledge translation projects to benefit the mental health of Ontarians. I am so grateful.”

Fellowship Funds to be Used to Improve the Mental and Physical Health Outcomes for Youth with Early Phase Psychosis in Ontario

This Fellowship will fill specific gaps in early phase psychosis treatment, including the prevention/management of metabolic syndrome in psychotic illnesses.

Dr. Saadia Sediqzadah’s knowledge translation goals include developing the first patient decision aid for early phase psychosis that will be co-designed by people with lived experience (PWLE), their families/caregivers and healthcare providers. Additionally, her qualitative research on antipsychotic-induced weight gain will result in the development of an online tool tailored to PWLE and healthcare providers. At the heart of her projects is the inclusion of PWLE with psychosis, following the mantra “nothing about us without us”.

2022 PSI Graham Farquharson KT Fellow at the Finish Line: Dr. Andrea Gershon Crosses the Endpoint

After a few years of tirelessly working towards their research program and knowledge translation (KT) activities, our PSI KT Fellows reach the finish line of their fellowship. As they cross the end point towards their award, we asked our fellows for reflections on their journey to share their highlights from the fellowship and advice for other aspiring or current KT Fellows.

What are the key accomplishments and outcomes from your award?

During the tenure of this award, I have achieved several meaningful accomplishment including:

  • Supporting Trainees: I have had the privilege of supervising and supporting a diverse group of trainees, including Master’s students, PhD candidates, medical residents, and postdoctoral fellows. Watching their growth and success has been one of the most rewarding aspects of this period.
  • Mentorship: Beyond direct supervision, I have provided mentorship to several new investigators across Canada, helping them establish their research programs and navigate early-career challenges.
  • Research Excellence: My work has led to a series of high-impact publications in leading journals, including the European Respiratory Journal, CMAJ, Chest, and Thorax. These publications have contributed to advancing the field and enhancing the visibility of our research program.
  • Knowledge Translation and Policy Impact: I have had opportunities to translate research into practice through collaborations with the Government of Ontario, the Canadian Thoracic Society, and the Lung Foundation. These partnerships have enabled our findings to inform policy and respiratory programs across the country.

What are some lessons learned during the PSI KT Fellowship?

One of the most valuable lessons I learned during the KT Fellowship is the importance of relationships with knowledge users. These relationships make research more relevant, meaningful, and impactful, and they truly energize a project. Engaging with our Respiratory Long COVID patient group was particularly inspiring — their insights, lived experiences, and enthusiasm shaped the direction of our work and reminded me of the real-world importance of translating research into action.

What were the most memorable moments of this PSI KT Fellowship?

Some of the most memorable moments of my KT Fellowship were watching my students achieve their goals. Seeing them publish their first papers, receive their first grants, or deliver their first conference presentations was incredibly rewarding — I felt proud to see their hard work and confidence grow.

Another highlight was working closely with patients, particularly those in our Respiratory Long COVID group. Their openness, resilience, and commitment to improving care brought a powerful sense of purpose to our work.

Finally, being recognized through awards during this period was both an honor and a reminder of the impact that collaborative, patient-centered research can have.

What are some general tips and advice you would give to those who are currently completing their KT Fellowship?

My main advice is to balance your projects — pursue some high-risk, high-reward ideas alongside more safe and steady ones. The ambitious projects push your boundaries and keep your work exciting, while the safer ones help build your track record and ensure steady progress. Early in my Fellowship, I took a risk by leading my first national prospective multicentre study, and it turned out to be an incredible learning experience that shaped my career.

I would also encourage fellows not to hesitate to take leadership positions. Leadership comes in many forms and personalities — you don’t have to fit a single mold to make an impact.

Dr. Malik Farooqi: Exploring Driving Pressure in Assisted Ventilation

“PSI’s funding gave me the resources and confidence to pursue a novel research project on better understanding patient-ventilator interaction. This project not only advanced our knowledge in the field but also helped shape my growth as a clinician-researcher, inspiring future projects and ongoing research.” –Dr. Malik Farooqi  

About Dr. Malik Farooqi

Dr. Malik Farooqi is an Assistant Clinical Professor (Adjunct) at McMaster University, a Critical Care Physician at William Osler Health System, and a Respirologist and Critical Care Physician at Niagara Health.

His research focuses on optimizing mechanical ventilation in the ICU setting.

About the Funded Study

Supported by the PSI Resident Research Grant, Dr. Farooqi set out to explore whether breathing effort and lung pressure could be reliably measured in patients receiving assisted ventilation in the intensive care unit (ICU). Working alongside his supervisor Dr. Bram Rochwerg, the study examined the feasibility of assessing driving pressure, a key marker of lung stress, in patients who are partially supported by a ventilator.

While high driving pressures are known to worsen outcomes for fully ventilated patients, their significance in those who still breathe on their own is still unclear. Drs. Farooqi and Rochwerg’s study “Driving Pressure in Assisted Ventilation as a Predictor for Successful Liberation from Invasive Mechanical Ventilation (DRIVE-SAFE)” demonstrated these measurements are possible and practical in the ICU setting. With a 90% success rate, their findings show that evaluating driving pressure and patient effort during assisted ventilation could provide valuable insights into lung function and patient recovery.

“PSI’s funding gave me the resources and confidence to pursue a novel research project on better understanding patient-ventilator interaction,” says Dr. Farooqi. “This project not only advanced our knowledge in the field but also helped shape my growth as a clinician-researcher, inspiring future projects and ongoing research.”

Impact of the Funded Study

The DRIVE-SAFE study achieved its goal of confirming the feasibility of measuring driving pressure and patient effort in ICU patients on assisted ventilation. The research revealed that patients with acute respiratory distress syndrome (ARDS) had higher mean driving pressures than non-ARDS patients, suggesting potential clinical implications for tailoring ventilation strategies.

Beyond advancing knowledge, this resident-led project has influenced critical care practice and education. The team has introduced workshops to train ICU residents, respiratory therapists, and staff in performing and interpreting these measurements, in turn promoting consistent, patient-centered ventilation practices. The study has also paved the way for multi-centre research to validate clinical benefits, such as improved weaning success rates and outcomes for ICU survivors.

The project earned first prize at the McMaster–Western University Critical Care Research Day (2023) and received provisional acceptance in CHEST: Critical Care Journal.

By demonstrating that measuring driving pressure is both feasible and clinically meaningful, Dr. Farooqi’s work represents an important step toward optimizing ventilation management and improving outcomes for critically ill patients.

 

Natasha Jawa: Improving ICU Care: Exploring How Dialysis Affects the Brain

“The PSI Research Trainee Fellowship Award has been instrumental in shaping my career as a clinician-scientist by providing the resources needed to investigate the neurocognitive outcomes of critically ill patients undergoing acute kidney replacement therapy (KRT).” -Natasha Jawa

About Natasha Jawa

Natasha (Tasha) Jawa is a MD candidate at Queen’s University. She recently completed her PhD and is now entering clinical clerkship in the sixth year of her MD/PhD program. Before her doctoral studies, she earned an HBSc in Neuroscience and Psychology and an MSc in Neuroscience & Quality Improvement/Patient Safety at the University of Toronto.

Her research focuses on the pathophysiological mechanisms underlying delirium in critically ill adults who are treated for acute kidney injury with kidney replacement therapy (KRT). She also examines the long-term consequences of ICU delirium on both cognitive function and structural brain pathology. In addition, Natasha seeks to evaluate whether a post-ICU follow-up bundle of care can improve long-term cognitive and psychosocial outcomes for ICU survivors and their caregivers.

About the Funded Study

With support from PSI, Natasha and her research supervisor, Dr. Gordon Boyd, set out to explore how acute kidney replacement therapy in the intensive care unit affects brain function. Although patients who undergo dialysis while critically ill often experience cognitive impairment, the relationship between dialysis and neurological outcomes is still poorly understood.

In their PSI-funded study, Identifying Neurocognitive Outcomes and Cerebral Oxygenation in Critically Ill Adults on Acute Kidney Replacement Therapy (INCOGNITO-AKI), Natasha and Dr. Boyd investigated how fluctuations in brain oxygenation during dialysis may influence short-term and long-term neurological outcomes.

While the study was limited by patient survival rates, the findings confirm tracking cerebral oxygenation in critically ill patients is feasible. This work emphasizes the importance of larger-scale studies to better gauge long-term cognitive outcomes and guide clinical strategies to minimize neurological impairments in patients undergoing dialysis.

Looking ahead, Natasha and Dr. Boyd plan to expand recruitment by enrolling patients earlier in their ICU stay and building multi-centre collaborations. They also aim to streamline enrollment using a deferred consent model and will continue investigating interventions to improve cerebral oxygenation during dialysis, with the goal of preventing cognitive decline.

“This funding has allowed me to establish and execute the INCOGNITO-AKI feasibility study, which has significantly contributed to my development in clinical research methodology, data analysis, and interdisciplinary collaboration,” says Natasha. “Furthermore, the award facilitated high-impact presentations at international and national conferences, increasing the visibility of my work within the nephrology, neuroscience, and critical care communities.”

Impact of the Funded Study

The INCOGNITO-AKI study has kickstarted an important discussion about an often overlooked aspect of patient care: neurocognitive function in critically ill patients receiving KRT. By highlighting the link between dialysis, brain oxygenation, and cognition, this research adds to a growing body of work on post-ICU cognitive impairment and supports efforts to improve care after critical illness.

Their future research hopes to expand to larger, multi-centre cohort studies to validate their results and identify modifiable risk factors. A longitudinal follow-up will be essential for them to assess persistent impairments after ICU discharge and guide rehabilitation. Natasha and Dr. Boyd also plan to test interventions such as optimized dialysis protocols and cognitive rehabilitation programs, while advanced neuroimaging will be used to study structural and functional brain changes in this patient population.

“Through this support, I have been able to advance my expertise in neurocognitive impairment, delirium, and various assessment tools for the longitudinal evaluation of neurological impairment in critically ill patients, positioning me for future research in this domain,” says Natasha.

Looking forward, Natasha’s work represents an important first step toward improving neurological outcomes in critically ill patients. By integrating neurocognitive monitoring into the management of KRT in the ICU, clinicians can move closer to treatment strategies that enhance both recovery and quality of life.

 

Dr. Christina Reppas-Rindlisbacher: Language Barriers and Hip Fracture Surgery Wait Times in Ontario

“The PSI Resident Research award enabled me to engage in high impact academic research during my residency — allowing me to explore how older adults from minority language groups experience different outcomes after hip fracture surgery.” –Dr. Christina Reppas-Rindlisbacher

About Dr. Christina Reppas-Rindlisbacher

Dr. Christina Reppas-Rindlisbacher is a Research Fellow at Women’s College Research Institute, and pursuing Geriatric Medicine at the University of Toronto. Currently, she is completing a PhD in Clinical Epidemiology & Health Care Research at the Institute of Health Policy, Management and Evaluation (IHPME). She received her medical degree from the University of Toronto, then completed her Internal Medicine residency at McMaster University.

Dr. Reppas-Rindlisbacher’s research interests includes uses of large administrative databases to study practice patterns and long-term adverse outcomes after delirium, with a focus on addressing the unmet needs of older adults who have immigrated to Canada or who have a preferred language other than English. Her work is supported by the University of Toronto Department of Medicine’s Eliot Phillipson Clinician-Scientist Training Program, and the CIHR Canadian Graduate Scholarships Masters Program award. Clinically, Dr. Reppas-Rindlisbacher focuses on acute geriatrics and attends on both the inpatient Geriatric Medicine Consultation Service and the Internal Medicine Clinical Teaching Units.

About the Funded Study

Hip fracture repair is the most common urgent surgery among older adults, making up more than 13,000 hospital admissions in Ontario each year. Hip fractures are often a catastrophic event associated with loss of independence and disability. As a result, hip fractures have been identified as a priority area for health quality improvement. Delays in surgeries to treat this are linked to increased complications, and even death–making timely access a provincial priority.

While longer waits are often associated with delays in diagnosis, consent, or administrative processes, Dr. Reppas-Rindlisbacher suspected another factor: language differences between patients and the healthcare system. Previous studies show that patients who speak a non-English language in predominantly English-speaking settings face more medical errors and receive lower quality of care.

With her PSI-funded study, Resident Researcher Dr. Reppas-Rindlisbacher, under the supervision of Dr. Paula Rochon, set out to explore how language barriers may contribute to longer wait times for hip fracture surgery. Their study, Association between language proficiency and wait time for hip fracture surgery in Ontario: a population-based study, addresses this gap by examining the impact of language preference on surgical wait times and care outcomes.

The study investigated whether non-English language preference affected time to surgery, as well as complications after the operation and discharge destination. Their findings revealed that older adults with a non-English language preference experienced longer waits and were at higher risk of delirium, myocardial infarction, prolonged hospital stays, and more often discharged to a nursing home post-surgery. These results are the first to show inequities in hip fracture care and treatment relating to language differences.

“It is crucial that older patients who speak non-English languages have the same opportunity for functional recovery and discharge home after hip fracture,” says Dr. Reppas-Rindlisbacher.

Impact of the Funded Study

The study’s findings and results highlight the disproportionate burden of harm faced by patients who do not speak or struggle to speak English. “Our findings are a call to action for hospitals to develop standards for language accessible care,” says Dr. Reppas-Rindlisbacher.

Moving forward, she identified steps that would improve care for hip fracture patients. This includes collecting patient language preference data; flagging those who require interpretation; training staff in the effective use of interpretation services; and expanding access to professional interpreters via video, phone, or in-person support.

Their research has already made a significant impact, including major accomplishments such as an oral abstract presentation at the American Geriatrics Society Annual Scientific Meeting, an Op-Ed in Healthing titled “Opinion: The language you speak shouldn’t impact the healthcare you receive,” and publication in JAMA Network Open.

Beyond publications and presentations, the study contributes to a growing body of evidence incentivizing hospitals to invest in interpretation services. It also lays the foundation for quality improvement initiatives aimed at reducing preventable complications and ensuring equitable recovery for patients from linguistically diverse backgrounds.

Looking ahead, the research team plans additional peer-reviewed publications, national and international conference presentations with complimentary Op-Eds. In addition, they aim to achieve knowledge translation through traditional media, social platforms, and collaborations with organizations like RTOERO–helping to share these findings with more than 81,000 members across Canada who may be directly impacted by hip fracture or language-differing care.

“The PSI Resident Research award enabled me to engage in high-impact academic research during my residency–allowing me to explore how older adults from minority language groups experience different outcomes after hip fracture surgery,” says Dr. Reppas-Rindlisbacher. “This project led to collaborations, conference presentations, and a high-impact publication in JAMA Network Open–all milestones that have shaped my career as a future geriatrician clinician scientist.”

 

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